Amends the Department of Human Services Act. Creates the Office to Prevent and End Homelessness (Office) within the Department of Human Services to facilitate the implementation of a strategic plan and initiatives aimed at decreasing homelessness and unnecessary institutionalization in Illinois, improving health and human services outcomes for people who experience homelessness, and strengthening the safety nets that contribute to housing stability. Provides that the Office shall be led by the State Homelessness Chief Officer who shall report to the Secretary of the Department. Provides that the Chief Officer shall also chair the Interagency Task Force on Homelessness, co-chair the Community Advisory Council on Homelessness, and lead the State's comprehensive efforts related to homelessness prevention. Creates the Interagency Task Force on Homelessness within the Department of Human Services to facilitate and implement initiatives related to decreasing homelessness and unnecessary institutionalization in this State, improving health and human services outcomes for people who experience homelessness, and strengthening the safety nets that contribute to housing stability. Sets forth the Task Force's specific duties. Requires the Task Force to submit annual reports to the Governor and General Assembly regarding the Task Force's work during the year prior, any new recommendations developed by the Task Force, any recommendations made by the Community Advisory Council on Homelessness, and any key outcomes and measures related to homelessness. Contains provisions concerning Task Force membership; Task Force meetings; Task Force subcommittees; administrative support to the Task Force; and other matters. Creates the Community Advisory Council on Homelessness (Advisory Council) within the Department of Human Services to make recommendations to the Interagency Task Force on Homelessness regarding homelessness and unnecessary institutionalization with the goals of achieving functional zero homelessness, improving health and human services outcomes for people experiencing homelessness and strengthening the safety nets that contribute to housing stability. Contains provisions concerning Advisory Council membership; Advisory Council meetings; administrative support to the Advisory Council; and other matters. Effective immediately.