Creates the Grocery Initiative Act. Provides that the Department of Commerce and Economic Opportunity shall study food insecurity in urban and rural food deserts. Provides that the Department shall establish a Grocery Initiative to expand access to healthy foods in food deserts in Illinois by providing assistance to independently owned for-profit grocery stores, as well as grocery stores owned and operated by local governmental units. Provides that the Department may enter into contracts, grants, or other agreements to administer grants and other financial support. Provides that the Department shall provide technical assistance. Provides the Department with rulemaking powers. Defines terms. Amends the Illinois Enterprise Zone Act. Provides that a business that is a grocery store and receives financial support under the Grocery Initiative Act during a specified period is eligible to be a High Impact Business.