Creates the Road Designation Program Act. Establishes a designation program for the naming and subsequent placement of signage upon interstate or State-numbered highway interchanges or upon bridges or segments of highway under the jurisdiction of the Department of Transportation. Provides that any person who desires to have roads designated or to erect signage upon designated roads must, in an application to the Department, state the total cost of construction and maintenance of the requested signage, as well as provide: (1) a description of the interstate or State-numbered highway interchange or bridge or segment of highway for which the designation is sought and the proposed name of the interchange, bridge, or relevant segment of highway; and (2) a letter of sponsorship from the State Representative and State Senator for each district in which the road is located. Provides that the Department shall give notice of any proposed designation on the Department's official public website. Provides that signs are subject to all applicable federal and State limitations or conditions on highway signage. Provides that 2 signs shall be erected for each interchange, bridge, or segment of highway designation and that all money received by the Department for the construction and maintenance of interchange, bridge, or segment of highway signs shall be deposited into the Road Fund. Effective immediately.